22-Oxacalcitriol

Tocris Bioscience | Catalog # 4160

Non-calcemic vitamin D3 (Cat. No. 4156) analog
Tocris Bioscience
Discontinued Product
4160 has been discontinued. View all Additional VDR-like Receptor Compounds products.

Key Product Details

Description

Non-calcemic vitamin D3 (Cat. No. 4156) analog

Alternative Names

Maxacalcitol
View all Additional VDR-like Receptor Compounds »

Product Description

22-Oxacalcitriol is a non-calcemic vitamin D3 (Cat. No. 4156) analog and VDR ligand. Suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Exhibits similar effects to calcitriol (Cat. No. 2551) in osteoblast-like cells. Inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid.

Product Specifications for 22-Oxacalcitriol

Molecular Weight

418.61

Formula

C26H42O4

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol

CAS Number

103909-75-7

PubChem ID

6398761

InChI Key

DTXXSJZBSTYZKE-ZDQKKZTESA-N

SMILES

C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](OCCC(C)(O)C)C)([H])/C2=C/C=C(C[C@@H](O)C[C@@H]1O)\C1=C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

Product Documents for 22-Oxacalcitriol

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for 22-Oxacalcitriol

For research use only

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