Chemical Name: (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
Biological Activity Non-calcemic vitamin D3 (Cat. No. 4156) analog and VDR ligand. Suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Exhibits similar effects to calcitriol (Cat. No. 2551) in osteoblast-like cells. Inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid.
Soluble in DMSO and in ethanol
Store at -20°C
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