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22-Oxacalcitriol

4160 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4160/1
22-Oxacalcitriol | CAS No. 103909-75-7 | Additional VDR-like Receptor Compounds
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Description: Non-calcemic vitamin D3 (Cat. No. 4156) analog
Alternative Names: Maxacalcitol

Chemical Name: (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol

Purity: ≥95%

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Biological Activity

Non-calcemic vitamin D3 (Cat. No. 4156) analog and VDR ligand. Suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Exhibits similar effects to calcitriol (Cat. No. 2551) in osteoblast-like cells. Inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid.

Technical Data

M.Wt:
418.61
Formula:
C26H42O4
Solubility:
Soluble in DMSO and in ethanol
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
103909-75-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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