Calcitriol

  ( 2 citations )    
Product Datasheet
Catalog Number:2551
Alternate Names:1,25-Dihydroxyvitamin D3
Chemical Name:(1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol
Product Details
Citations (2)
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Biological Activity
Active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Displays calcemic actions; stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Exhibits antitumor activity; inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells.
Technical Data
  • M.Wt:
    416.64
  • Formula:
    C27H44O3
  • Solubility:
    Soluble in DMSO and in ethanol
  • Purity:
    >99
  • Storage:
    Desiccate at -20°C
  • CAS No:
    32222-06-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Calcitriol include:

2 Citations: Showing 1 - 2
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  1. A novel cytostatic form of autophagy in sensitization of non-small cell lung cancer cells to radiation by vitamin D and the vitamin D analog, EB 1089.
    Authors: Sharma Et al.
    Atherosclerosis  2015;10:2346
  2. Osteocalcin positive mononuclear cells are associated with the severity of aortic calcification.
    Authors: Pal Et al.
    J Neurosci  2010;210:88

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