Non-selective voltage-dependent K+
-channel blocker (IC50
values are 170 and 230 μ
M at KV
1.1 and KV
1.2 respectively). Caged 4-AP
(Cat. No. 3557) is also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Closed and open state binding of 4-aminopyridine to the cloned human potassium channel Kv1.5.
Bouchard and Fedida
In vitro electrophysiological activity of nerispirdine, a novel 4-aminopyridine derivative.
Smith et al.
Reverse use dependence of Kv4.2 blockade by 4-aminopyridine.
Tseng et al.
Different state dependencies of 4-aminopyridine binding to rKv1.4 and rKv4.2: role of the cytoplasmic halves of the fifth and sixth transmembrane segments.
The citations listed below are publications that use Tocris products. Selected citations for 4-Aminopyridine include:
Showing Results 1 - 10 of 21