Inhibitor of macrophage migration inhibitory factor (MIF). Acts as a suicide substrate to inactivate MIF catalytic and biological functions; inhibits MIF-associated liver enzyme activity in vivo
. Also inhibits migration and anchorage independence of human lung adenocarcinoma cell lines in vitro
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A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells.
Winner et al.
Cancer Res., 2008;68:7253
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