4-Methylhistamine dihydrochloride

  ( 4 citations )    
Product Datasheet
Catalog Number:2342
Chemical Name:5-(2-Aminoethyl)-4-methylimidazole dihydrochloride
Product Details
Citations (4)
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Reviews
Biological Activity
Potent, high affinity H4 receptor agonist (Ki = 7 nM) that displays > 100-fold selectivity over other human histamine receptor subtypes.
Technical Data
  • M.Wt:
    198.09
  • Formula:
    C6H11N3.2HCl
  • Solubility:
    Soluble to 50 mM in water
  • Storage:
    Desiccate at RT
  • CAS No:
    36376-47-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for 4-Methylhistamine dihydrochloride include:

4 Citations: Showing 1 - 4
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  1. Effects of histamine on cultured interstitial cells of cajal in murine small intestine.
    Authors: Kim Et al.
    Korean J Physiol Pharmacol  2013;17:149
  2. Histamine H4 receptor antagonists as potent modulators of mammalian vestibular primary neuron excitability.
    Authors: Desmadryl Et al.
    Br J Pharmacol  2012;167:905
  3. The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS.
    Authors: Connelly Et al.
    Br J Pharmacol  2009;157:55
  4. Potentiation of NF-κB-dependent transcription and inflammatory mediator release by histamine in human airway epithelial cells.
    Authors: Holden Et al.
    Bone Joint Res  2007;152:891

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