4-P-PDOT

  ( 7 citations )    
Product Datasheet
Catalog Number:1034
Alternate Names:AH 024
Chemical Name:cis-4-Phenyl-2-propionamidotetralin
Product Details
Citations (7)
Supplemental Products
Reviews
Biological Activity
Melatonin receptor antagonist, >300-fold selective for the MT2 (vs MT1) subtype.
Technical Data
  • M.Wt:
    279.38
  • Formula:
    C19H21NO
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    620170-78-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for 4-P-PDOT include:

7 Citations: Showing 1 - 7
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  1. Homeostatic Plasticity Mediated by Rod-Cone Gap Junction Coupling in Retinal Degenerative Dystrophic RCS Rats.
    Authors: Hou Et al.
    Front Cell Neurosci  2017;11:98
  2. Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain.
    Authors: Chen Et al.
    J Clin Invest  2014;20:1298
  3. MT2 receptors mediate the inhibitory effects of melatonin on nitric oxide-induced relaxation of porcine isolated coronary arteries.
    Authors: Tunstall Et al.
    J Pharmacol Exp Ther  2011;336:127
  4. Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis.
    Authors: Jones Et al.
    Biochem Pharmacol  2010;80:1478
  5. Melatonin potentiates glycine currents through a PLC/PKC signalling pathway in rat retinal ganglion cells.
    Authors: Zhao Et al.
    J Physiol  2010;588:2605
  6. Melatonin stimulates cell proliferation in zebrafish embryo and accelerates its development.
    Authors: Danilova Et al.
    J Pharmacol Exp Ther  2004;18:751
  7. Peripheral melatonin mediates neural stimulation of duodenal mucosal bicarbonate secretion.
    Authors: Sjöblom Et al.
    FASEB J  2001;108:625

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