4-P-PDOT
Tocris Bioscience | Catalog # 1034
Key Product Details
Description
Alternative Names
Product Description
4-P-PDOT is a melatonin receptor antagonist, >300-fold selective for the MT2 (vs MT1) subtype.
Product Specifications for 4-P-PDOT
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 27.94 | 100 | |
| Ethanol | 27.94 | 100 |
Preparing Stock Solutions for 4-P-PDOT
The following data is based on the product molecular weight 279.38.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.58 mL | 17.90 mL | 35.79 mL |
| 5 mM | 0.72 mL | 3.58 mL | 7.16 mL |
| 10 mM | 0.36 mL | 1.79 mL | 3.58 mL |
| 50 mM | 0.07 mL | 0.36 mL | 0.72 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 49 publications citing the usage of this product.
- Dubocovich Melatonin receptors: are there multiple subtypes? TiPS 1995 PMID: 7762083
- Dubocovich Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroceptor. Naunyn Schmiedebergs Arch.Pharmacol. 1997 PMID: 9089668
Product Documents for 4-P-PDOT
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for 4-P-PDOT
For research use only
Citations for 4-P-PDOT
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