53BP2 Antibody

Name: 53BP2 Antibody
Brand: Novus Biologicals
SKU: NB100-2858
Price: 459 USD
Availability: InStock

Novus Biologicals | Catalog # NB100-2858

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

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Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 425 and 475 of human Apoptosis-Stimulating Protein of p53, 2 (53BP2) using the numbering given in entry NP_001026855.1 (GeneID 7159).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for 53BP2 Antibody

Western Blot: 53BP2 Antibody [NB100-2858]

Western Blot: 53BP2 Antibody [NB100-2858] - Detection of Human ASPP2 on HeLa whole cell lysates using NB100-2858. ASPP2 was also immunoprecipitated by rabbit anti-ASPP2 antibody NB100-2859.

Applications for 53BP2 Antibody

Application

Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: 53BP2

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternate Names

apoptosis-stimulating protein of p53, 2, ASPP2P53BP2,53BP2apoptosis-stimulating of p53 protein 2, Bbp, Bcl2-binding protein, p53-binding protein 2, p53BP2, PPP1R13A, Renal carcinoma antigen NY-REN-51, tumor protein p53 binding protein, 2, tumor protein p53-binding protein, 2, Tumor suppressor p53-binding protein 2

Entrez Gene IDs

7159 (Human)

Gene Symbol

TP53BP2

UniProt

NP_001026855.1 (Human)

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Product Documents for 53BP2 Antibody

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Certificate of Analysis

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Product Specific Notices for 53BP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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