Cell permeable cAMP analog; selectively activates cAMP-dependent PKA but not Epac signaling pathways. Acts synergistically with 8-CPT-2Me-cAMP
(Cat. No. 1645) to inhibit vascular smooth muscle cell proliferation.
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All Tocris products are intended for laboratory research use only.
PKA and Epac synergistically inhibit smooth muscle cell proliferation.
Hewer et al.
J.Mol.Cell Cardiol., 2011;50:87