Chemical Name: 7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide
Biological ActivityInhibitor of eukaryotic elongation factor-2 (eEF-2) kinase (IC50 = 0.28 μM in enzymatic assay). Reduces eEF-2 phosphorylation with little effect on cancer cell growth.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Citation for A 484954
The citations listed below are publications that use Tocris products. Selected citations for A 484954 include:
1 Citation: Showing 1 - 1
The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Authors: Bouhaddou Et al.
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