Home / CaM Kinase Inhibitors / A 484954

A 484954

4483 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4483/10
4483/50
A 484954 | CAS No. 142557-61-7 | CaM Kinase Inhibitors
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Description: CaM kinase III (eEF-2 kinase) inhibitor

Chemical Name: 7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide

Purity: ≥98%

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Biological Activity

Inhibitor of eukaryotic elongation factor-2 (eEF-2) kinase (IC50 = 0.28 μM in enzymatic assay). Reduces eEF-2 phosphorylation with little effect on cancer cell growth.

Technical Data

M.Wt:
289.29
Formula:
C13H15N5O3
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
142557-61-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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