Chemical Name: 7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide
Biological ActivityA 484954 is an inhibitor of eukaryotic elongation factor-2 (eEF-2) kinase (IC50 = 0.28 μM in enzymatic assay). Reduces eEF-2 phosphorylation with little effect on cancer cell growth.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Citation for A 484954
The citations listed below are publications that use Tocris products. Selected citations for A 484954 include:
1 Citation: Showing 1 - 1
The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Authors: Bouhaddou Et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for A 484954
There are currently no reviews for this product. Be the first to review A 484954 and earn rewards!
Have you used A 484954?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image