A 484954
Chemical Name: 7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide
Purity: ≥98%
Biological Activity
A 484954 is an inhibitor of eukaryotic elongation factor-2 (eEF-2) kinase (IC50 = 0.28 μM in enzymatic assay). Reduces eEF-2 phosphorylation with little effect on cancer cell growth.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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Citation for A 484954
The citations listed below are publications that use Tocris products. Selected citations for A 484954 include:
1 Citation: Showing 1 - 1
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The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Authors: Bouhaddou Et al.
Cell 2020;182:685
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