Inhibitor of eukaryotic elongation factor-2 (eEF-2) kinase (IC50
= 0.28 μ
M in enzymatic assay). Reduces eEF-2 phosphorylation with little effect on cancer cell growth.
Soluble to 10 mM in DMSO
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor.