A 582941

Catalog # Availability Size / Price Qty
4341/10
4341/50
Nicotinic (a7) Receptor Agonists Small Molecule
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Description: α7 nAChR partial agonist

Chemical Name: Octahydro-2-methyl-5-(6-phenyl-3-pyridazinyl)-pyrrolo[3,4-c]pyrrole

Purity: ≥98%

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Biological Activity

Selective α7 nAChR partial agonist; exhibits high affinity for both rat and human α7 receptors (Ki values are 10.8 and 16.7 nM respectively). Displays ~15-fold selectivity for α7 over 5-HT3 receptors (Ki = 150 nM for 5-HT3).

Technical Data

M.Wt:
280.37
Formula:
C17H20N4
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
848591-90-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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