-adrenoceptor agonist that is at least 35-fold more potent at α1A
than at α1B
sites. Induces dose response increases in spontaneous Ca2+
transients in rat ventricular myocytes in vitro
= 6.9 nmol/L). Also available as part of the α1-Adrenoceptor Tocriset™
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
A-61603, a potent α1-adrenergic receptor agonist, selective for the α1A receptor subtype.
Knepper et al.
Receptor subtype involved in α1A-adrenergic receptor-mediated Ca2+ signaling in cardiomyocytes.
Luo et al.
Synthesis and in vitro characterisation of N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide and its enantiomers: a novel selective α1A receptor agonist.
Meyer et al.
The citations listed below are publications that use Tocris products. Selected citations for A 61603 hydrobromide include:
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