A 61603 hydrobromide

Tocris Bioscience | Catalog # 1052

α1A agonist
Tocris Bioscience

Key Product Details

Description

α1A agonist
View all Adrenergic alpha-1 Receptor Agonists »

Product Description

A 61603 hydrobromide is a potent α-adrenoceptor agonist that is at least 35-fold more potent at α1A than at α1B or α1D sites. Induces dose response increases in spontaneous Ca2+ transients in rat ventricular myocytes in vitro (EC50 = 6.9 nmol/L).

Product Specifications for A 61603 hydrobromide

Molecular Weight

390.29

Formula

C14H19N3O3S.HBr

Storage

Desiccate at +4°C

Chemical Name

N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide hydrobromide

CAS Number

107756-30-9

PubChem ID

9865178

InChI Key

LRFLWCZMTGTUEP-UHFFFAOYSA-N

SMILES

Br.CS(=O)(=O)NC1=C(O)C=CC2=C1CCCC2C1=NCCN1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 50

Preparing Stock Solutions for A 61603 hydrobromide

The following data is based on the product molecular weight 390.29.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 5.12 mL 25.62 mL 51.24 mL
2.5 mM 1.02 mL 5.12 mL 10.25 mL
5 mM 0.51 mL 2.56 mL 5.12 mL
25 mM 0.10 mL 0.51 mL 1.02 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 21 publications citing the usage of this product.

Product Documents for A 61603 hydrobromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for A 61603 hydrobromide

For research use only

Citations for A 61603 hydrobromide

Customer Reviews for A 61603 hydrobromide (1)

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  • A61603 works well on H9C2
    Name: Anonymous
    Assay Type: In Vitro
    Cell Line/Tissue: H9C2
    Verified Customer | Posted 08/20/2018
    A61603 was used to treat H9C2 for 24hours, works well as intended.

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