hh A-71623 (CAS 130408-77-4): R&D Systems
Catalog Number: 2411
Chemical Name: N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophyl-N6-[[(2-methylphenyl)amino]carbonyl]-L-lysyl-L-α-aspartyl-Nα-methyl-L-phenylalaninamide
Biological Activity
Potent CCK1 agonist (IC50 = 3.7 nM) with 1200-fold selectivity over the CCK2 receptor. Suppresses food intake following central or peripheral administration.
Technical Data
  • M.Wt:
    840.97
  • Formula:
    C44H56N8O9
  • Sequence:
    XWKDF

    (Modifications: Trp-1 = Boc-Trp, Lys-3 = Lys(Tac), Phe-5 = N-methyl-Phe & C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in 20mM PBS buffer
  • Storage:
    Desiccate at -20°C
  • CAS No:
    130408-77-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. A-71623, a selective CCK-A receptor agonist, suppresses food intake in the mouse, dog, and monkey.
    Asin et al.
    Pharmacol.Biochem.Behav., 1992;42:699
  2. Development of CCK-tetrapeptide analogues as potent and selective CCK-A receptor agonists.
    DeNinno et al.
    J.Med.Chem., 1990;33:2951

Have you used A-71623?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information