Biological Activity Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor (IC50 = 60 nM). Displays no effect on calcineurin, protein PP-1 or APTX. Interrupts DNA repair and enhances radiosensitivity of human A549 lung carcinoma and MDA-MB-231 cells.
Soluble to 100 mM in DMSO
Store at +4°C
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For batch specific data refer to the Certificate of Analysis.
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