A66

Catalog # Availability Size / Price Qty
5595/50
5595/10
Cat.No. 5595 - A66 | C17H23N5O2S2 | CAS No. 1166227-08-2
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Description: Potent and selective PI 3-kinase p110α inhibitor

Chemical Name: (2S)-N1-[2-(1,1-Dimethylethyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide

Purity: ≥98%

Product Details
Reviews

Biological Activity

Potent and selective PI 3-kinase p110α inhibitor (IC50 = 32 nM). Exhibits >100-fold selectivity for p110α over other PI 3-kinase isoforms. Inhibits Akt signaling and tumor growth in SK-OV-3 xenografts in mice.

Technical Data

M.Wt:
393.53
Formula:
C17H23N5O2S2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1166227-08-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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