ABP 688

Catalog # Availability Size / Price Qty
5229/50
5229/10
Cat.No. 5229 - ABP 688 | C15H16N2O | CAS No. 924298-51-1
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Description: High affinity human mGlu5 receptor antagonist

Chemical Name: 3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime

Purity: ≥98%

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Biological Activity

High affinity human mGlu5 receptor antagonist (Ki = 1.7 nM). Inhibits glutamate-induced calcium release from L(tk-) cells expressing human mGlu5 receptors (IC50 = 2.3 nM).

Technical Data

M.Wt:
240.3
Formula:
C15H16N2O
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
924298-51-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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