Chemical Name: 3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime
Biological ActivityHigh affinity human mGlu5 receptor antagonist (Ki = 1.7 nM). Inhibits glutamate-induced calcium release from L(tk-) cells expressing human mGlu5 receptors (IC50 = 2.3 nM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies.
Hintermann et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
VersaClone cDNA Plasmids
Reviews for ABP 688
There are currently no reviews for this product. Be the first to review ABP 688 and earn rewards!
Have you used ABP 688?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image