AC 253

Catalog # Availability Size / Price Qty
6550/1
Cat.No. 6550 - AC 253 | Ac-Leu-Gly-Arg-Leu-Ser-Gln-Glu-Leu-His-Arg-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2 | CAS No. 151804-79-4
1 Image
Description: Amylin (AMY3) receptor antagonist
Product Details
Reviews

Biological Activity

Amylin (AMY3) receptor antagonist. Inhibits andrenomedulin-stimulated cAMP production in vitro. Protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. Blocks electrophysiological effects of Aβ in vitro. Cyclic AC 253 (Cat.No. 6550) also available.

Technical Data

M.Wt:
2847.11
Formula:
C122H196N40O39
Sequence:
LGRLSQELHRLQTYPRTNTGSNTY

(Modifications: Leu-1 = N-terminal Ac, Tyr-24 = C-terminal amide)

Solubility:
Soluble to 2 mg/ml in water
Storage:
Store at -20°C
CAS No:
151804-79-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

Reviews for AC 253

There are currently no reviews for this product. Be the first to review AC 253 and earn rewards!

Have you used AC 253?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.