ACE/CD143 Antibody (ACE/7004R)

Name: ACE/CD143 Antibody (ACE/7004R)
Brand: Novus Biologicals
SKU: NBP3-13863
Price: 469 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-13863

Submit a review

Product Documents

Recombinant Monoclonal Antibody

View Available Conjugates View Available Formulations

100% Guarantee

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # ACE/7004R

View all ACE/CD143 Primary Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa 652-788) of human ACE/CD143 protein (Uniprot: P12821)

Localization

Cell Surface

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

150 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-14036)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.

Applications for ACE/CD143 Antibody (ACE/7004R)

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

ELISA: For coating, order antibody without BSA

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: ACE/CD143

ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

Long Name

Angiotensin I Converting Enzyme

Alternate Names

CD143, DCP1, Kininase II

Gene Symbol

ACE

UniProt

P12821

Additional ACE/CD143 Products

Product Documents for ACE/CD143 Antibody (ACE/7004R)

Download Product Datasheets

Download SDS

Product Specific Notices for ACE/CD143 Antibody (ACE/7004R)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.