Acetazolamide

Key Product Details

Product Description

Acetazolamide is a carbonic anhydrase inhibitor. Modulates epileptiform synchronization in rat brain slices. Increases speed of synaptic vesicle recycling and changes synaptic performance in ex vivo murine neuromuscular junction. Lowers intracranial pressure in healthy rats. Also potentiates the antitumor effects of the HDAC inhibitor MS 275 (Cat. No. 6208).

Product Specifications for Acetazolamide

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Acetazolamide

The following data is based on the product molecular weight 222.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.50 mL	22.50 mL	44.99 mL
5 mM	0.90 mL	4.50 mL	9.00 mL
10 mM	0.45 mL	2.25 mL	4.50 mL
50 mM	0.09 mL	0.45 mL	0.90 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

• Hamidi Carbonic anhydrase inhibition by acetazol. reduces in vitro epileptiform synchronization. Neuropharmacology. 2015 PMID: 25937211
• Uldall Acetazolamide lowers intracranial pressure and modulates the cerebrospinal fluid secretion pathway in healthy rats. Neurosci.Lett. 2017 PMID: 28219789
• Bertone Carbonic anhydrase inhibitor acetazol. shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction. Synapse. 2017 PMID: 28873252
• Bayat Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma. BMC Cancer. 2017 PMID: 28235409

Product Documents for Acetazolamide