MS 275

Catalog # Availability Size / Price Qty
MS 275 | CAS No. 209783-80-2 | Class I Histone Deacetylases Inhibitors
1 Image
Description: HDAC (Class I) inhibitor
Alternative Names: entinostat, SNDX 275

Chemical Name: (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate

Purity: ≥99%

Product Details
Citations (1)

Biological Activity

MS 275 is a class I HDAC inhibitor (IC50 values are 0.18, 0.74, 44.9 and >100 μM for HDAC1, 3, 8 and 6, respectively). Exhibits antiproliferative effects and induces apoptosis in a range of tumor cell lines in vitro and in vivo. Increases estrogen receptor α- and aromatase expression in breast cancer cells. Inhibits PCB-induced neuronal cell death by preventing HDAC3 binding and histone deacetylation within the synapsin-1 promoter.

Technical Data

Soluble to 100 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for MS 275

The citations listed below are publications that use Tocris products. Selected citations for MS 275 include:

1 Citation: Showing 1 - 1


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for MS 275

There are currently no reviews for this product. Be the first to review MS 275 and earn rewards!

Have you used MS 275?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.