ADAMTS4 Antibody (1#) - BSA Free

Novus Biologicals | Catalog # NBP3-41648

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa/IgG1 Kappa Clone # 1#

Format

BSA Free
View all ADAMTS4 Primary Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human ADAMTS4 (Uniprot#: O75173; Thr437-Pro575 (Uniprot#: O75173)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa/IgG1 Kappa

Description

Novus Biologicals Mouse ADAMTS4 Antibody (1#) - BSA Free (NBP3-41648) is a monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for ADAMTS4 Antibody (1#) - BSA Free

ADAMTS4 Antibody (1#)

Western Blot: ADAMTS4 Antibody (1#) [NBP3-41648] -

Western Blot: ADAMTS4 Antibody (1#) [NBP3-41648] - Sample: Recombinant ADAMTS4, Human.

Applications for ADAMTS4 Antibody (1#) - BSA Free

Application
Recommended Usage

Western Blot

0.01-2ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Format

BSA Free

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ADAMTS4

ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan and the brain extracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signal sequence, a propeptide domain, a catalytic domain, a disintegrin-like motif, and a C-terminal domain with a thrombospondin (TSP) type 1 motif. ADAMTS4 has been implicated in inflammatory joint diseases, and it also may be a factor in the progression of glioma and Alzheimer's disease. ADAMTS4 expression has been documented in normal human brain, cartilage, heart, lung, placenta, muscle, and synovium. ESTs have been isolated from human tissue libraries, including normal brain, lung, pancreas, and skeletal muscle and cancerous breast.

Long Name

A Disintegrin-like and Metalloproteinase Domain with Thrombospondin Motifs 4

Alternate Names

ADMP-1, Aggrecanase 1

Gene Symbol

ADAMTS4

Additional ADAMTS4 Products

Product Documents for ADAMTS4 Antibody (1#) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ADAMTS4 Antibody (1#) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Metalloproteases and Regulators

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