Afadin/AF-6 Antibody [PE]

Name: Afadin/AF-6 Antibody [PE]
Brand: Novus Biologicals
SKU: AF7829P
Price: 549 USD
Availability: InStock

Novus Biologicals | Catalog # AF7829P

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot, Immunocytochemistry

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Polyclonal Sheep IgG

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Product Specifications

Immunogen

E. coli-derived recombinant human Afadin/AF-6
Asn217-Pro392
Accession # P55196

Specificity

Detects human Afadin/AF-6 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human METTL-11A is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Afadin/AF-6 Antibody [PE]

Application

Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Afadin/AF-6

AF6/Afadin was identified as part of a fusion with MLL (mixed lineage leukemia) in a t(6;11) genetic translocation. AF6/Afadin is also known as afadin (a splicing variant of AF6/Afadin found at adherins junction). AF6/afadin is an actin filament binding protein that binds to nectin at cadherin-based cell-cell adherens junctions and regulates cell-cell adhesion by mediating Ras signaling.

Alternate Names

AF-6, AF6, AFAD, MLLT4

Gene Symbol

AFDN

Additional Afadin/AF-6 Products

Product Documents for Afadin/AF-6 Antibody [PE]

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Product Specific Notices for Afadin/AF-6 Antibody [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.