Human AGTR-2 ELISA Kit (Colorimetric)

Novus Biologicals | Catalog # NBP2-69083

Novus Biologicals
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Key Product Details

Sample Type & Volume Required Per Well

Serum, plasma and other biological fluids (100 uL)

Sensitivity

0.10 ng/mL

Assay Range

0.16 - 10 ng/mL
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Product Specifications

Assay Type

Sandwich-ELISA

Kit Type

ELISA Kit (Colorimetric)

Species

Human

Specificity

This kit recognizes Human AGTR-2 in samples. No significant cross-reactivity or interference between Human ANGIIR2 and analogues was observed.

Precision

Intra-Assay Precision (Precision within an assay) CV% 5.93%

Inter-Assay Precision (Precision between assays) CV% 4.87%

Recovery for Human AGTR-2 ELISA Kit (Colorimetric)

Recovery

83-108%

Linearity

Human AGTR-2 ELISA Kit (Colorimetric)

Scientific Data Images for Human AGTR-2 ELISA Kit (Colorimetric)

Human AGTR-2 ELISA Kit (Colorimetric)

ELISA: Human AGTR-2 ELISA Kit (Colorimetric) [NBP2-69083] -

ELISA: Human AGTR-2 ELISA Kit (Colorimetric) [NBP2-69083] - Standard Curve Reference

Kit Contents for Human AGTR-2 ELISA Kit (Colorimetric)

  • Biotinylated Detection Ab Diluent
  • Concentrated Biotinylated Detection Ab (100x)
  • Concentrated HRP Conjugate (100x)
  • Concentrated Wash Buffer (25x)
  • HRP Conjugate Diluent
  • Micro ELISA Plate (Dismountable)
  • Plate Sealer
  • Product Manual
  • Reference Standard
  • Sample Diluent
  • Stop Solution
  • Substrate Reagent

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: AGTR-2

Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5; untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame.

Long Name

Angiostensin II Type 2 Receptor

Alternate Names

AGTR2, AT2, AT2R, MRX88

Gene Symbol

AGTR2

Additional AGTR-2 Products

Product Documents for Human AGTR-2 ELISA Kit (Colorimetric)

Certificate of Analysis

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Product Specific Notices for Human AGTR-2 ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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