Catalog Number: 5256
Chemical Name: 4-Methyl-N-9H-xanthen-9-yl-benzenesulfonamide
Biological Activity
Selective free fatty acid receptor 4 (FFA4/GPR120) antagonist (pIC50 values are 7.1 and <4.6 for human FFA4 and FFA1 receptors respectively). Inhibits linoleic acid and GSK 137647A-induced intracellular calcium accumulation in U2OS osteosarcoma cells expressing the FFA4 receptor.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline
Background References
  1. Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).
    Sparks et al.
    Bioorg.Med.Chem.Lett., 2014;24:3100
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