AH 7614

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5256/10
5256/50
AH 7614 | CAS No. 6326-06-3 | Free Fatty Acid Receptor Antagonists
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Description: Selective FFA4 (GPR120) antagonist

Chemical Name: 4-Methyl-N-9H-xanthen-9-yl-benzenesulfonamide

Purity: ≥98%

Product Details
Citations (2)
Supplemental Products
Reviews

Biological Activity

Selective free fatty acid receptor 4 (FFA4/GPR120) antagonist (pIC50 values are 7.1 and <4.6 for human FFA4 and FFA1 receptors respectively). Inhibits linoleic acid and GSK 137647A-induced intracellular calcium accumulation in U2OS osteosarcoma cells expressing the FFA4 receptor.

Technical Data

M.Wt:
351.42
Formula:
C20H17NO3S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
6326-06-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline

Background References

  1. Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).
    Sparks et al.
    Bioorg.Med.Chem.Lett., 2014;24:3100

Product Datasheets

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Citations for AH 7614

The citations listed below are publications that use Tocris products. Selected citations for AH 7614 include:

2 Citations: Showing 1 - 2

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