Selective free fatty acid receptor 4 (FFA4/GPR120) antagonist (pIC50
values are 7.1 and <4.6 for human FFA4 and FFA1 receptors respectively). Inhibits linoleic acid and GSK 137647A
-induced intracellular calcium accumulation in U2OS osteosarcoma cells expressing the FFA4 receptor.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold for research purposes under agreement from GlaxoSmithKline
Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).
Sparks et al.