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3 results for "Free Fatty Acid Receptor Antagonists" in Products
Free Fatty Acid Receptor Antagonists
Free Fatty Acid (FFA) receptors are a group of Gq/11 protein-coupled receptors that are currently classified into FFA1, FFA2, FFA3 and FFA4 subtypes. FFA receptors are concentrated in the pancreatic islet cells (particularly FFA1) and in the brain, with lower expression levels found in adipose tissue, peripheral blood mononuclear cells, neutrophils and monocytes.
FFAs 1, 2 and 3 genes are co-located on chromosome 19 and have closely related sequences, while FFA4 is located on chromosome 10 and ...
Selective FFA4 (GPR120) antagonist
| Chemical Name: | 4-Methyl-N-9H-xanthen-9-yl-benzenesulfonamide |
| Purity: | ≥98% |
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FFA1 (GPR40) antagonist
| Chemical Name: | N-(4-Butylphenyl)-4-fluorobenzenesulfonamide |
| Purity: | ≥98% |
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Potent FFA2 (GPR43) antagonist
| Chemical Name: | 4-[[[(2R)-1-(Benzo[b]thien-3-ylcarbonyl)-2-methyl-2-azetidinyl]carbonyl][(3-chlorophenyl)methyl]amino]butanoic acid |
| Purity: | ≥98% |
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