AIF Antibody (3C11) - BSA Free

Novus Biologicals | Catalog # NBP2-50606

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 3C11

Format

BSA Free
View all AIF Primary Antibodies »

Product Specifications

Immunogen

AIF-His fusion protein

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for AIF Antibody (3C11) - BSA Free

Western Blot: AIF Antibody (3C11)BSA Free [NBP2-50606]

Western Blot: AIF Antibody (3C11)BSA Free [NBP2-50606]

Western Blot: AIF Antibody (3C11) [NBP2-50606] - Western blot was performed on transfected 293T cell lysates using anti-AIF [3C11].

Applications for AIF Antibody (3C11) - BSA Free

Application
Recommended Usage

Western Blot

1:100 - 1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AIF

AIF, or apoptosis-inducing factor, is a flavoprotein localized to the mitochondrial membrane that plays a primary role in caspase-independent cell death, or apoptosis (1,2). AIF translocates to the nucleus when apoptosis is induced and causes mitochondria to release the apoptogenic proteins, cytochrome c and caspase-9. Apoptotic activity of AIF leads to chromatin condensation and DNA fragmentation (1). Similar to cytochrome c, AIF is a bifunctional protein with an oxidoreductase function and a second apoptogenic function. In contrast to cytochrome c, however, AIF acts in a caspase-independent fashion (2,3,4).

Long Name

Apoptosis Inducing Factor

Alternate Names

AIFM1, COXPD6, PDCD8

Gene Symbol

AIFM1

Additional AIF Products

Product Documents for AIF Antibody (3C11) - BSA Free

Certificate of Analysis

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Product Specific Notices for AIF Antibody (3C11) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Bcl-2 Proteins and Regulators

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FAQs

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Associated Pathways

Apoptosis Signaling Pathway Apoptosis Signaling Pathway Thumbnail