Human AKR1B1 ELISA Kit (Colorimetric)

Novus Biologicals | Catalog # NBP2-60536

Novus Biologicals
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Key Product Details

Sample Type & Volume Required Per Well

Serum, Plasma, Cell Culture (50 uL (example only; lot dependent))

Sensitivity

70 pg/mL (example only; lot dependent)

Assay Range

0.156 - 10 ng/ml (example only; lot dependent)
View all AKR1B1 ELISA Kits »

Product Specifications

Assay Type

Sandwich ELISA

Kit Type

ELISA Kit (Colorimetric)

Species

Human

Description

This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.

Precision

Intra-Assay Precision (Precision within an assay) CV% 5.10% (example only; lot dependent)

Inter-Assay Precision (Precision between assays) CV% 9.90% (example only; lot dependent)

Recovery for Human AKR1B1 ELISA Kit (Colorimetric)

Recovery

86-115% (example only; lot dependent)

Scientific Data Images for Human AKR1B1 ELISA Kit (Colorimetric)

ELISA: Human AKR1B1 ELISA Kit (Colorimetric) [NBP2-60536]

ELISA: Human AKR1B1 ELISA Kit (Colorimetric) [NBP2-60536]

ELISA: Human Aldose Reductase Inhibitors ELISA Kit (Colorimetric) [NBP2-60536] - Standard curve.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: AKR1B1

Aldose reductase (also designated AKR1B1, ALDR1, ALR2 or AR) is member of the monomeric NADPH-dependent aldoketoreductase family. Aldose reductase, which has a molecular mass of 36 kDa, catalyzes the reduction of various aldehydes and has been implicated in the development of diabetic complications by catalyzing the reduction of the aldehyde form of glucose, to the corresponding sugar alcohol, sorbitol. This pathway plays a minor role in glucose metabolism in most tissues, however in diabetic hyperglycemia, cells undergoing insulin-independent uptake of glucose accumulate significant quantities of sorbitol. The resulting hyperosmotic stress to cells may be a cause of diabetic complications such as neuropathy, retinopathy, and cataracts. Aldose reductase is very similar to human aldehyde reductase, bovine prostaglandin F synthase and to the European common frog protein, rho-crystallin.

Alternate Names

ADR, Aldehyde reductase, Aldo-keto reductase family 1 member B1, aldo-keto reductase family 1, member B1 (aldose reductase), ALDR1aldose reductase, ALR2, ARaldehyde reductase 1, EC 1.1.1, EC 1.1.1.21, Lii5-2 CTCL tumor antigen, low Km aldose reductase, MGC1804

Gene Symbol

AKR1B1

Additional AKR1B1 Products

Product Documents for Human AKR1B1 ELISA Kit (Colorimetric)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Human AKR1B1 ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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