AL 8697

Catalog # Availability Size / Price Qty
4753/10
4753/50
AL 8697 | CAS No. 1057394-06-5 | p38 Inhibitors
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Description: Potent and selective p38α inhibitor

Chemical Name: N-Cyclopropyl-3-[3-(1,1-dimethylethyl)-6,8-difluoro-1,2,4-triazolo[4,3-a]pyridin-7-yl]-5-fluoro-4-methylbenzamide

Purity: ≥98%

Product Details
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Biological Activity

Potent and selective p38α inhibitor (IC50 = 6 nM). Exhibits 14-fold greater inhibition of p38α compared to p38β; also displays 300-fold selectivity for p38α compared to a panel of 91 kinases. Exhibits anti-inflammatory properties.

Technical Data

M.Wt:
402.41
Formula:
C21H21F3N4O
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1057394-06-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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