[Ala11,D-Leu15]-Orexin B

Tocris Bioscience | Catalog # 2142

Potent and selective OX2 agonist
Tocris Bioscience

Key Product Details

Description

Potent and selective OX2 agonist
View all OX2 Receptor Agonists »

Product Description

[Ala11,D-Leu15]-Orexin B is a highly potent and selective OX2 receptor agonist; displays 400-fold selectivity over OX1 receptors. EC50 values are 0.13 and 52 nM for human OX2 and OX1 receptors respectively.

Product Specifications for [Ala11,D-Leu15]-Orexin B

Molecular Weight

2857.28

Formula

C120H206N44O35S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

532932-99-3

PubChem ID

16201464

InChI Key

SURUUKNICBOUOQ-JNZZMZGCSA-N

SMILES

[H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 0.3mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.

Product Documents for [Ala11,D-Leu15]-Orexin B

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for [Ala11,D-Leu15]-Orexin B

For research use only

Citations for [Ala11,D-Leu15]-Orexin B

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