[Ala11,D-Leu15]-Orexin B

Catalog # Availability Size / Price Qty
2142/1
[Ala11,D-Leu15]-Orexin B
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Description: Potent, selective OX2 receptor agonist
Product Details
Citations (4)
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Biological Activity

Highly potent and selective OX2 receptor agonist; displays 400-fold selectivity over OX1 receptors. EC50 values are 0.13 and 52 nM for human OX2 and OX1 receptors respectively.

Technical Data

M.Wt:
2857.28
Formula:
C120H206N44O35S
Sequence:
RSGPPGLQGRAQRLLQASGNHAAGILTM

(Modifications: Met-28 = C-terminal amide)

Solubility:
Soluble to 0.30 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
532932-99-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Development of an orexin-2 receptor selective agonist, [Ala11D-Leu15]orexin-B.
    Asahi et al.
    Bioorg.Med.Chem.Lett., 2003;13:111

Product Datasheets

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Citations for [Ala11,D-Leu15]-Orexin B

The citations listed below are publications that use Tocris products. Selected citations for [Ala11,D-Leu15]-Orexin B include:

4 Citations: Showing 1 - 4

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