[Ala92]-p16 (84-103)
Tocris Bioscience | Catalog # 1902
Cdk 4 inhibitor peptide; derived from p16
Discontinued Product
1902 has been discontinued.
View all Cyclin-dependent Kinase Inhibitors products.
Key Product Details
Description
Cdk 4 inhibitor peptide; derived from p16
Product Description
[Ala92]-p16 (84-103) is a peptide derived from the tumor suppressor protein p16; inhibits cyclin-dependent kinase-4 (cdk4)/cyclin D1 (IC50 ~ 1.5 μM) and binds to cdk6.
Product Specifications for [Ala92]-p16 (84-103)
Molecular Weight
2123.44
Formula
C93H155N31O26
Storage
Desiccate at -20°C
CAS Number
189064-08-2
PubChem ID
71308539
InChI Key
SRSWQMWUNOIPDH-QCDQIEFZSA-N
SMILES
[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 2mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product.
- Fahraeus Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule. Oncogene 1998 PMID: 9482104
Product Documents for [Ala92]-p16 (84-103)
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for [Ala92]-p16 (84-103)
For research use only
Related Research Areas
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