Catalog Number: 1902
Biological Activity
Peptide derived from the tumor suppressor protein p16; inhibits cyclin-dependent kinase-4 (cdk4)/cyclin D1 (IC50 ~ 1.5 μM) and binds to cdk6.
Technical Data
  • M.Wt:
    2123.44
  • Formula:
    C93H155N31O26
  • Sequence:
    DAAREGFLATLVVLHRAGAR
  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    189064-08-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule.
    Fahraeus et al.
    Oncogene, 1998;16:587

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