ALDH18A1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-30292

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all ALDH18A1 Primary Antibodies »

Product Specifications

Immunogen

Between 745 and 795

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ALDH18A1 Antibody - BSA Free

ALDH18A1 Antibody

Immunoprecipitation:ALDH18A1 AntibodyNBP3-30292] -

Immunoprecipitation:ALDH18A1 AntibodyNBP3-30292] -Detection of human ALDH18A1/P5CS by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-ALDH18A1/P5CS antibody NBP3-30292 (lot NBP3-30292-1) used for IP at 6 µg per reaction. ALDH18A1/P5CS was also immunoprecipitated by rabbit anti-ALDH18A1/P5CS.. For blotting immunoprecipitated ALDH18A1/P5CS, NBP3-30292 was used at 0.4 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

Applications for ALDH18A1 Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate pH 7 -8.

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ALDH18A1

ALDH18A1, or Delta-1-pyrroline-5-carboxylate synthase, contains a long 88 kDa and a short 87 kDa isoform, and is involved in the catalytic conversion of glutamate to glutamate 5-semialdehyde. Current research on ALDH18A1 is being conducted to determine the relation between the protein and a variety of diseases and disorders, including neurodegeneration, pneumonia, connective tissue disease, mental retardation, hypoornithinemia, tuberculosis, microcephaly, Alzheimer's disease, gastroesophageal reflux disease, and dementia. The protein has been linked to biosynthesis and metabolic pathways where it interacts with PUS1, UQCRFS1, ICT1, OAT, and MYC.

Alternate Names

aldehyde dehydrogenase 18 family, member A1, Aldehyde dehydrogenase family 18 member A1, delta-1-pyrroline-5-carboxylate synthase, EC 2.1.2.11, EC 2.3.3.13, GSASdelta1-pyrroline-5-carboxlate synthetase, MGC117316, P5CSdelta-1-pyrroline-5-carboxylate synthetase, PYCSEC 1.2.1.41, pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)

Gene Symbol

ALDH18A1

Additional ALDH18A1 Products

Product Documents for ALDH18A1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for ALDH18A1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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