alpha Endosulfine Antibody (S08-1G6)

Novus Biologicals | Catalog # NBP3-14992

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-1G6 expressed in HEK293
View all alpha Endosulfine Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human alpha Endosulfine (Uniprot#: O43768)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

15 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for alpha Endosulfine Antibody (S08-1G6)

Western Blot: alpha Endosulfine Antibody (S08-1G6) [NBP3-14992]

Western Blot: alpha Endosulfine Antibody (S08-1G6) [NBP3-14992]

Western Blot: alpha Endosulfine Antibody (S08-1G6) [NBP3-14992] - Western blot detection of alpha Endosulfine in Rat Brain, C6, 3T3, Hela cell lysates using alpha Endosulfine Rabbit mAb (1:1000 diluted). Predicted band size: 13kDa. Observed band size: 15kDa.

Applications for alpha Endosulfine Antibody (S08-1G6)

Application
Recommended Usage

Western Blot

1/1000-1/5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha Endosulfine

alpha Endosulfine is encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. alpha Endosulfine is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternate Names

alpha-endosulfine, ARPP-19eMGC4319, endosulfine alpha, MGC78563, MGC8394

Gene Symbol

ENSA

Additional alpha Endosulfine Products

Product Documents for alpha Endosulfine Antibody (S08-1G6)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for alpha Endosulfine Antibody (S08-1G6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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