An analog of retinoic acid that acts as a selective RARα
values are 0.3, 8.6 and 13 nM for RARα
respectively). Significantly induces IL-4, IL-5 and IL-13 and inhibits IL-12 and IFNγ
synthesis, and induces cell differentiation with over 7 times the activity of retinoic acid in vitro
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All Tocris products are intended for laboratory research use only.
Retinobenzoic acids. 1. Structure-activity relationships of aromatic amides with retinoidal activity.
Kagechika et al.
Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.
Charton et al.
The retinoic acid receptor-α mediates human T-cell activation and Th2 cytokine and chemokine production.
Dawson et al.
BMC Immunol., 2008;9:16
Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1.
Wang et al.
The citations listed below are publications that use Tocris products. Selected citations for AM 580 include:
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