Aminoguanidine hydrochloride

Key Product Details

Product Description

Aminoguanidine hydrochloride is a irreversible inhibitor of iNOS that displays some selectivity over eNOS and nNOS. Exhibits antioxidant and radioprotective effects in vivo.

Product Specifications for Aminoguanidine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Aminoguanidine hydrochloride

The following data is based on the product molecular weight 110.55.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	9.05 mL	45.23 mL	90.46 mL
5 mM	1.81 mL	9.05 mL	18.09 mL
10 mM	0.90 mL	4.52 mL	9.05 mL
50 mM	0.18 mL	0.90 mL	1.81 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Moore and Handy Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 1997 PMID: 9226999
• Huang Aminoguanidine alleviates radiation-induced small-bowel damage through its antioxidant effect. Int.J.Radiat.Oncol.Biol.Phys. 2009 PMID: 19362242
• Laszlo Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo. Eur.J.Pharmacol. 1995 PMID: 7536162
• Griffiths Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br.J.Pharmacol. 1993 PMID: 7507781

Product Documents for Aminoguanidine hydrochloride