Aminoguanidine hydrochloride (CAS 1937-19-5): R&D Systems
Catalog Number: 0787
Biological Activity
Irreversible inhibitor of iNOS that displays some selectivity over eNOS and nNOS. Exhibits antioxidant and radioprotective effects in vivo.
Technical Data
  • M.Wt:
    110.55
  • Formula:
    CH6N4.HCl
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Store at RT
  • CAS No:
    1937-19-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Aminoguanidine alleviates radiation-induced small-bowel damage through its antioxidant effect.
    Huang et al.
    Int.J.Radiat.Oncol.Biol.Phys., 2009;74:237
  2. Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo.
    Laszlo et al.
    Eur.J.Pharmacol., 1995;272:169
  3. Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system?
    Moore and Handy
    TiPS, 1997;18:204
  4. Aminoguanidine selectively inhibits inducible nitric oxide synthase.
    Griffiths et al.
    Br.J.Pharmacol., 1993;110:963
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Aminoguanidine hydrochloride include:

1 Citations: Showing 1 - 1

  1. Nitric oxide signals are interlinked with calcium signals in normal pancreatic stellate cells upon oxidative stress and inflammation.
    Authors: Jakubowska Et al.
    Open Biol. 2016;6:160149

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