Irreversible inhibitor of iNOS that displays some selectivity over eNOS and nNOS. Exhibits antioxidant and radioprotective effects in vivo
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All Tocris products are intended for laboratory research use only.
Aminoguanidine alleviates radiation-induced small-bowel damage through its antioxidant effect.
Huang et al.
Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo.
Laszlo et al.
Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system?
Moore and Handy
Aminoguanidine selectively inhibits inducible nitric oxide synthase.
Griffiths et al.