L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca
-induced contractions in depolarized rat aorta (IC
= 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Calcium channel blocking properties of amlodipine in vascular smooth muscle and cardiac muscle in vitro: evidence for voltage modulation of vascular dihydropyridine receptors.
Burges et al.
Antiproliferative effect of Ca 2+ channel blockers on human epidermoid carcinoma A431 cells.
Yoshida et al.
Calcium channel blockades exhibit anti-inflammatory and antioxidative effects by augmentation of endothelial nitric oxide synthase and the inhibition of angiotensin converting enzyme in the N-nitro-L-arginine methyl ester-induced hype G
Toba et al.
The citations listed below are publications that use Tocris products. Selected citations for Amlodipine besylate include:
1 Citations: Showing 1 - 1
Have you used Amlodipine besylate?
Submit a Review
Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.