Amyloid β-peptide (42-1) (human)
Biological ActivityAmyloid β-peptide (42-1) (human) is an inactive control peptide for amyloid β-peptide (1-42), the predominant form of amyloid β-peptide found in the brains of patients with Alzheimer's disease.
Active Analog also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Amyloid-beta peotide is toxic to neurons in vivo via indirect mechanisms.
Walsh et al.
Mitochondrial respiratory inhibition and oxidative stress elevate β-secretase (BACE1) proteins and activity in vivo in the rat retina.
Xiong et al.
Exp.Brain Res., 2007;181:435
Proteomic identification of proteins oxidized by Aβ(1-42) in synaptosomes: Implications for Alzheimer's disease.
Boyd-Kimball et al.
Brain Res., 2005;1004:206
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