Potent and selective TMEM16A (Anoctamin-1; ANO1) blocker (IC50
= 77 nM). Displays no effect on ANO2 activity (at 10 μ
M). Also exhibits no effect on intracellular calcium signaling or CFTR and ENaC channel activity (at 30 μ
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Ani9, a novel potent small-molecule ANO1 inhibitor with negligible effect on ANO2.
Seo et al.
PLoS One, 2016;11:e0155771