Ani 9

Key Product Details

Product Description

Ani 9 is a potent and selective TMEM16A (Anoctamin-1; ANO1) blocker (IC₅₀ = 77 nM). Displays no effect on ANO2 activity (at 10 μM). Also exhibits no effect on intracellular calcium signaling or CFTR and ENaC channel activity (at 30 μM).

Product Specifications for Ani 9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Ani 9

The following data is based on the product molecular weight 332.78.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.00 mL	15.02 mL	30.05 mL
5 mM	0.60 mL	3.00 mL	6.01 mL
10 mM	0.30 mL	1.50 mL	3.00 mL
50 mM	0.06 mL	0.30 mL	0.60 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 33 publications citing the usage of this product.

• Seo Ani9, a novel potent small-molecule ANO1 inhibitor with negligible effect on ANO2. PLoS One 2016 PMID: 27219012

Product Documents for Ani 9