Catalog Number: 6076
Chemical Name: 2-(4-Chloro-2-methylphenoxy)-N'-(2-methoxybenzylidene)acetohydrazide
Biological Activity
Potent and selective TMEM16A (Anoctamin-1; ANO1) blocker (IC50 = 77 nM). Displays no effect on ANO2 activity (at 10 μM). Also exhibits no effect on intracellular calcium signaling or CFTR and ENaC channel activity (at 30 μM).
Technical Data
  • M.Wt:
    332.78
  • Formula:
    C17H17ClN2O3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    356102-14-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Ani9, a novel potent small-molecule ANO1 inhibitor with negligible effect on ANO2.
    Seo et al.
    PLoS One, 2016;11:e0155771
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