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Ani 9

Catalog #: 6076 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6076/50
6076/10
Ani 9 | CAS No. 356102-14-2 | Calcium-activated Chloride Channel Blockers
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Description: Potent and selective TMEM16A (Anoctamin-1; ANO1) blocker

Chemical Name: 2-(4-Chloro-2-methylphenoxy)-N'-(2-methoxybenzylidene)acetohydrazide

Purity: ≥98%

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Biological Activity

Ani 9 is a potent and selective TMEM16A (Anoctamin-1; ANO1) blocker (IC50 = 77 nM). Displays no effect on ANO2 activity (at 10 μM). Also exhibits no effect on intracellular calcium signaling or CFTR and ENaC channel activity (at 30 μM).

Technical Data

M.Wt:
332.78
Formula:
C17H17ClN2O3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
356102-14-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Complete Your Experiment

CaCCinh-A01
Cat # 4877

Background References

  1. Ani9, a novel potent small-molecule ANO1 inhibitor with negligible effect on ANO2.
    Seo et al.
    PLoS One, 2016;11:e0155771

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