AS 8351

Catalog # Availability Size / Price Qty
6044/5
6044/25
Cat.No. 6044 - AS 8351 | C17H13N3O2 | CAS No. 796-42-9
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Description: Induces reprogramming of fibroblasts into functional cardiomyocytes

Chemical Name: 2-Hydroxy-1-naphthaldehyde isonicotinoylhydrazone

Purity: ≥98%

Product Details
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Biological Activity

Induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes, in combination with CHIR 99021, A83-01, BIX 01294, SC1, Y-27632, OAC2, SU 16f and JNJ 10198409. Iron chelator and putative inhibitor of KDM5B.

Technical Data

M.Wt:
291.3
Formula:
C17H13N3O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
796-42-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Background References

  1. Conversion of human fibroblasts into functional cardiomyocytes by small molecules.
    Cao et al.
    Science, 2016;352:6290

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