Chemical Name: 2-Hydroxy-1-naphthaldehyde isonicotinoylhydrazone
Biological ActivityInduces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes, in combination with CHIR 99021, A83-01, BIX 01294, SC1, Y-27632, OAC2, SU 16f and JNJ 10198409. Iron chelator and putative inhibitor of KDM5B.
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Conversion of human fibroblasts into functional cardiomyocytes by small molecules.
Cao et al.
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