AS 8351

Tocris Bioscience | Catalog # 6044

Induces reprogramming of fibroblasts into functional cardiomyocytes
Tocris Bioscience
Discontinued Product
6044 has been discontinued. View all Additional Stem Cell Dedifferentiation Products products.

Key Product Details

Description

Induces reprogramming of fibroblasts into functional cardiomyocytes

Product Description

AS 8351 is an induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes, in combination with CHIR 99021, A83-01, BIX 01294, SC1, Y-27632, OAC2, SU 16f and JNJ 10198409. Iron chelator and putative inhibitor of KDM5B.

Product Specifications for AS 8351

Molecular Weight

291.30

Formula

C17H13N3O2

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-Hydroxy-1-naphthaldehyde isonicotinoylhydrazone

CAS Number

796-42-9

PubChem ID

5353827

InChI Key

UBECDIQQXGETMR-PTNGSMBKSA-N

SMILES

OC1=C(C2=CC=CC=C2C=C1)/C=N/NC(C3=CC=NC=C3)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 29.13 100

Preparing Stock Solutions for AS 8351

The following data is based on the product molecular weight 291.30.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.43 mL 17.16 mL 34.33 mL
5 mM 0.69 mL 3.43 mL 6.87 mL
10 mM 0.34 mL 1.72 mL 3.43 mL
50 mM 0.07 mL 0.34 mL 0.69 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for AS 8351

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for AS 8351

For research use only

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