SU 16f

Catalog # Availability Size / Price Qty
3304/10
3304/50
SU 16f | CAS No. 251356-45-3 | PDGF Receptor Inhibitors
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Description: Potent and selective PDGFRβ inhibitor

Chemical Name: 5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid

Purity: ≥98%

Product Details
Citations (4)
Supplemental Products
Reviews

Biological Activity

Potent and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor (IC50 = 10 nM) that displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. Inhibits proliferation of HUVEC and NIH3T3 cells in vitro (IC50 = 0.11 μM).

Technical Data

M.Wt:
386.44
Formula:
C24H22N2O3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
251356-45-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for SU 16f

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