SU 16f

  ( 2 citations )    
Product Datasheet
Catalog Number:3304
Chemical Name:5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid
Product Details
Citations (2)
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Biological Activity
Potent and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor (IC50 = 10 nM) that displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. Inhibits proliferation of HUVEC and NIH3T3 cells in vitro (IC50 = 0.11 μM).
Technical Data
  • M.Wt:
    386.44
  • Formula:
    C24H22N2O3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    251356-45-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for SU 16f include:

2 Citations: Showing 1 - 2
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  1. Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells.
    Authors: Andersen Et al.
    Proc Natl Acad Sci U S A  2015;6:196
  2. Lymphatic endothelial cells support tumor growth in breast cancer.
    Authors: Lee Et al.
    Sci Rep  2014;4:5853

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