Chemical Name: 2-Acetoxybenzoic acid
Biological ActivityAspirin is an inhibitor of cyclooxygenase (COX)-1. Blocks the production of prostaglandins and thromboxanes. Exhibits antiplatelet and antithrombotic activities. Displays anticancer effects in some solid tumors. One of the first described NSAID drugs.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells.
Sanduja et al.
Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis.
Aspirin and cancer.
Preventative Medicine, 1995;24:121
Citations for Aspirin
The citations listed below are publications that use Tocris products. Selected citations for Aspirin include:
2 Citations: Showing 1 - 2
The role of Nox1 and Nox2 in GPVI-dependent platelet activation and thrombus formation.
Authors: Walsh Et al.
Redox Biol 2014;2:178
A novel and essential role for FcγRIIa in cancer cell-induced platelet activation.
Authors: Mitrugno Et al.
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