-adrenergic receptor antagonist (Ki
values are 1.1, 1.0, 0.89, 1300 and 6500 nM for α2A
receptors respectively). Brain penetrant.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Highly selective and specific antagonism of central and peripheral alpha 2-adrenoceptors by atipamezole.
Virtanen et al.
An α2-adrenergic antagonist, atipamezole, facilitates behavioral recovery after focal cerebral ischemia in rats.
Puurunen et al.
α2A adrenergic receptor activation inhibits epileptiform activity in the rat hippocampal CA3 region.
Jurgens et al.
The citations listed below are publications that use Tocris products. Selected citations for Atipamezole hydrochloride include:
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