Atipamezole hydrochloride

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Atipamezole hydrochloride | CAS No. 104075-48-1 | Adrenergic alpha-2 Receptor Antagonists
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Description: Selective α2 antagonist

Chemical Name: 5-(2-Ethyl-2,3-dihydro-1H-indene-2-yl)-1H-imidazole hydrochloride

Product Details
Citations (2)
Supplemental Products
Reviews (1)

Biological Activity

Selective α2-adrenergic receptor antagonist (Ki values are 1.1, 1.0, 0.89, 1300 and 6500 nM for α2A, α2B, α2C, α1A and α1B receptors respectively). Brain penetrant.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
Store the unopened product at room temperature. Do not use past expiration date.

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Atipamezole hydrochloride

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behavioral pharmacology in rats
By Corinne Kiessling on 01/04/2018
Species: Rat

Behavioral neuropharmacology. Atimpamezole (0.1-1.0 mg/mL) was dissolved in 50-100% DMSO and was injected systemically in rats. Atipamezole is highly selective for the alpha2- noradrenergic receptor, and was used as a reference compound during behaviral testing.

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