Human ADRA2C (NP_000674) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Human ADRA2C (NP_000674) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: alpha-2C Adrenergic R/ADRA2C

Alpha-2-adrenergic receptors, including ADRA2C, are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C receptors that have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Mouse studies have revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The ADRA2A subtype inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.

Long Name
Alpha-2C Adrenergic Receptor
Entrez Gene IDs
152 (Human); 11553 (Mouse); 24175 (Rat)
Alternate Names
a-2C AdrenergicR; ADRA2C; ADRA2L2; ADRA2L2alpha-2CAR; ADRA2RL2; ADRARL2; adrenergic, alpha-2C-, receptor; Alpha-2 adrenergic receptor subtype C4; alpha2-AR-C4; alpha-2C Adrenergic R; alpha-2C adrenergic receptor; alpha2C AdrenergicR; Alpha-2C adrenoceptor; Alpha-2C adrenoreceptor; alpha-2C-adrenergic receptor; ALPHA2CAR; Alpha-2CAR


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