Atosiban

Catalog # Availability Size / Price Qty
6332/10
Atosiban
1 Image
Description: Potent oxytocin receptor antagonist
Product Details
Citations (1)
Reviews

Biological Activity

Atosiban is a potent oxytocin receptor (OTR) antagonist. Inhibits oxytocin-induced increase in Ca2+ concentration in myometrial cells in vitro (IC50 = 5 nM) Activates NF-κB and MAPK pathways in human amnion via Gαi signaling, resulting in pro-inflammatory effects. Inhibits oxytocin-induced uterine contractions in vivo and in vitro. Effective in a rat preterm labor model.

Technical Data

M.Wt:
994.19
Formula:
C43H67N11O12S2
Sequence:
XYITNCPXG

(Modifications: X-1 = Mpr, Tyr-2 = D-Tyr(OEt), X-8 = Orn, Gly-9 = C-terminal amide, Cyclized: X-1 - Cys-6)

Solubility:
Soluble to 100 mg/ml in water
Storage:
Store at -20°C
CAS No:
90779-69-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for Atosiban

The citations listed below are publications that use Tocris products. Selected citations for Atosiban include:

1 Citation: Showing 1 - 1

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

Reviews for Atosiban

There are currently no reviews for this product. Be the first to review Atosiban and earn rewards!

Have you used Atosiban?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.