A selective and potent GluR5 kainate receptor agonist (Ki
= 4.3 nM), inactive at GluR6 (Ki
> 1 mM) and only weakly active at AMPA receptors (GluR1-4) and the kainate receptors KA-2 and GluR7 (Ki
values of 6 - 14 μ
M). Also available as part of the Kainate Receptor Tocriset™
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission.
Clarke et al.
AMPA receptor agonists: synthesis, protolytic properties, and pharmacology of 3-isothiazole bioisasteres of glutamic acid.
Matzen et al.
Excitotoxic injury profiles of low-affinity kainate receptor agonists in neuronal cultures.
Moldrich et al.
The citations listed below are publications that use Tocris products. Selected citations for ATPA include:
Showing Results 1 - 5 of 5