AZD 2066

Tocris Bioscience | Catalog # 5614

mGlu5 antagonist; orally bioavailable and brain penetrant
Tocris Bioscience

Key Product Details

Description

mGlu5 antagonist; orally bioavailable and brain penetrant
View all Group I mGluR Antagonists »

Product Description

AZD 2066 is an mGlu5 antagonist. Displays discriminative effects in rats. Orally bioavailable and brain penetrant.

Product Specifications for AZD 2066

Molecular Weight

381.82

Formula

C19H16ClN5O2

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

4-[5-[(1R)-1-[5-(3-Chlorophenyl)-3-isoxazolyl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl]pyridine

CAS Number

934282-55-0

PubChem ID

16041426

InChI Key

SXWHYTICXCLKDG-GFCCVEGCSA-N

SMILES

CN1C(C2=CC=NC=C2)=NN=C1O[C@H](C)C3=NOC(C4=CC=CC(Cl)=C4)=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 38.18 100
Ethanol 38.18 100

Preparing Stock Solutions for AZD 2066

The following data is based on the product molecular weight 381.82.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.62 mL 13.10 mL 26.19 mL
5 mM 0.52 mL 2.62 mL 5.24 mL
10 mM 0.26 mL 1.31 mL 2.62 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for AZD 2066

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for AZD 2066

For research use only

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