Banoxantrone dihydrochloride

Catalog # Availability Size / Price Qty
4219/5
4219/25
Banoxantrone dihydrochloride | CAS No. 252979-56-9 | DNA Topoisomerase Inhibitors
1 Image
Description: Prodrug topoisomerase II inhibitor
Alternative Names: AQ4N

Chemical Name: 1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione dihydrochloride

Purity: ≥98%

Product Details
Reviews

Biological Activity

Bioreductive prodrug; activated by hypoxia to yield the topoisomerase II inhibitor AQ4. Displays little to no cytotoxic activity against 60 tumor cell lines tested under oxic conditions (IC50 >100 μM). Exhibits anti-tumor efficacy in vivo when combined with oxic cell cytotoxins; enhances the anti-tumor effect of cyclophosphamide (Cat. No. 4091) in a mouse tumor model.

Technical Data

M.Wt:
517.4
Formula:
C22H28N4O6.2HCl
Solubility:
Soluble to 50 mM in water and to 25 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
252979-56-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Banoxantrone dihydrochloride

There are currently no reviews for this product. Be the first to review Banoxantrone dihydrochloride and earn rewards!

Have you used Banoxantrone dihydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.