Bax channel blocker

  ( 1 citations )    
Product Datasheet
Catalog Number:2160
Chemical Name:3,6-Dibromo-α-(1-piperazinylmethyl)-9H-carbazole-9-ethanol dihydrochloride
Product Details
Citations (1)
Reviews
Biological Activity
Potent inhibitor of Bax-mediated mitochondrial cytochrome c release (IC50 = 0.52 μM). Suggested to inhibit Bax channel formation/activity.
Technical Data
  • M.Wt:
    540.12
  • Formula:
    C19H21Br2N3O.2HCl
  • Solubility:
    Soluble to 5 mM in water and to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Desiccate at RT
  • CAS No:
    329349-20-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Bax channel blocker include:

1 Citations: Showing 1 - 1

  1. Feedback activation of AMPK-mediated autophagy acceleration is a key resistance mechanism against SCD1 inhibitor-induced cell growth inhibition.
    Authors: Ono Et al.
    PLoS One  2017;12:e0181243

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