BAY 707

Catalog # Availability Size / Price Qty
BAY 707 | CAS No. 2109805-96-9 | MTH1 Inhibitors
1 Image
Description: Potent and selective MTH1 inhibitor

Chemical Name: N-Ethyl-4-[(3S)-3-methyl-4-morpholinyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

Purity: ≥98%

Product Details

Biological Activity

BAY 707 is a potent and selective MTH1 inhibitor (IC50 = 2.3 nM); exhibits no significant activity at 1 μM concentration against a panel of 97 kinases. BAY 707 is cell-permeable and active in vivo, and displays no antitumor activity in vitro or in vivo.

External Portal Information is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of BAY 707 is reviewed on the chemical probes website.

Technical Data

Soluble to 100 mM in DMSO and to 10 mM in ethanol
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the BAY-707 probe summary on the SGC website.

Product Datasheets

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