Chemical Name: 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid
Biological ActivityInhibitor of L-type amino acid transporter LAT1. Suppresses growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells.
Kim et al.
L-type amino acid transporter-1 overexpression and melphalan sensitivity in Barrett's adenocarcinoma.
Lin et al.
L-type amino acid transporters in two intestinal epithelial cell lines function as exchangers with neutral amino acids.
Fraga et al.
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