Human SLC7A5/LAT1 (NP_003477) VersaClone cDNA

R&D Systems | Catalog # RDC1463

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Key Product Details

Species

Human

Accession Number

NP_003477

Background: SLC7A5/LAT1

Mammalian cells have several amino acid transport systems. These systems have been defined by both activity and specific genes. L-type amino acid transporter 1 (LAT1) is a 12 membrane-spanning protein. LAT1 is a Na + -independent neutral amino acid transporter agency and essential for the transporter of large neutral amino acid such as Leucine, Isoleucine, and Valine through the plasma membrane. LAT1 has been proposed to be one of the major nutrient transport systems at the blood-brain barrier. Drugs such as L Dopa are transported by LAT1. LAT1 is thought to be up-regulated to support the high protein synthesis for cell growth in some tumor cell lines.

Long Name

Solute Carrier Family 7 Member 5

Alternate Names

4F2LC, CD98lc, E16, LAT1, MPE16, TA1

Entrez Gene IDs

8140 (Human); 20539 (Mouse); 50719 (Rat)

Gene Symbol

SLC7A5

UniProt

NP_003477

Additional SLC7A5/LAT1 Products

Product Documents for Human SLC7A5/LAT1 (NP_003477) VersaClone cDNA

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Product Specific Notices for Human SLC7A5/LAT1 (NP_003477) VersaClone cDNA

For research use only

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