Home / Apoptosis Inducer Compounds / Bendamustine hydrochloride

Bendamustine hydrochloride

3681 1 Review Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3681/10
3681/50
Bendamustine hydrochloride | CAS No. 3543-75-7 | Apoptosis Inducer Compounds
1 Image
Description: Cytostatic agent; exhibits DNA alkylating and purine analog properties

Chemical Name: 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride

Purity: ≥98%

Product Details
Reviews (1)
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Cytostatic agent that displays activity in non-Hodgkin's lymphomas. Exhibits bifunctionality; combines DNA alkylating properties with those of purine analogs.

Technical Data

M.Wt:
394.72
Formula:
C16H21Cl2N3O2.HCl
Solubility:
Soluble to 25 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
3543-75-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Bendamustine.
    Keating et al.
    Nat.Rev.Drug Discov., 2008;7:473
  2. Bendamustine therapy in chronic lymphocytic leukemia.
    Masiello and Tulpule
    Expert Opin.Pharmacother., 2009;10:1687
  3. In vitro evaluation of bendamu. induced apoptosis in B-chronic lymphocytic leukemia.
    Schwanen et al.
    Leukemia., 2002;16:2096

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Bendamustine hydrochloride

Average Rating: 5 (Based on 1 Review)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used Bendamustine hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Bendamustine termporarily halts growth of melanoma cells in vitro
By Anonymous on 02/14/2019
Application: Species: Human

Bendamustine was used at a 20 uM concentration for in vitro culture with SK-MEL-28 and cell viability was monitored over time with live imaging. Arrow indicates when compound was added to media.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.