Bendamustine hydrochloride

Tocris Bioscience | Catalog # 3681

Cytostatic agent; exhibits DNA alkylating and purine analog properties
Tocris Bioscience
Discontinued Product
3681 has been discontinued. View all Apoptosis Inducer Compounds products.

Key Product Details

Description

Cytostatic agent; exhibits DNA alkylating and purine analog properties
View all Apoptosis Inducer Compounds »

Product Description

Bendamustine hydrochloride is a cytostatic agent that displays activity in non-Hodgkin's lymphomas. Exhibits bifunctionality; combines DNA alkylating properties with those of purine analogs.

Product Specifications for Bendamustine hydrochloride

Molecular Weight

394.72

Formula

C16H21Cl2N3O2.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride

CAS Number

3543-75-7

PubChem ID

77082

InChI Key

ZHSKUOZOLHMKEA-UHFFFAOYSA-N

SMILES

CN2C1=CC=C(N(CCCl)CCCl)C=C1N=C2CCCC(O)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 9.87 25
DMSO 39.47 100

Preparing Stock Solutions for Bendamustine hydrochloride

The following data is based on the product molecular weight 394.72.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.53 mL 12.67 mL 25.33 mL
5 mM 0.51 mL 2.53 mL 5.07 mL
10 mM 0.25 mL 1.27 mL 2.53 mL
50 mM 0.05 mL 0.25 mL 0.51 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Bendamustine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Bendamustine hydrochloride

For research use only

Citations for Bendamustine hydrochloride

Customer Reviews for Bendamustine hydrochloride (1)

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  • Bendamustine termporarily halts growth of melanoma cells in vitro
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 02/14/2019
    Bendamustine was used at a 20 uM concentration for in vitro culture with SK-MEL-28 and cell viability was monitored over time with live imaging. Arrow indicates when compound was added to media.
    Bendamustine hydrochloride 3681

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